Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Compazine, Stemetil, Prochlorperazine Edisylate, Prochlorperazine Maleate
Prochlorperazine is an antipsychotic medication primarily used to treat schizophrenia and other psychotic disorders. It belongs to the phenothiazine class of drugs and works by blocking dopamine receptors in the brain. It is also effective in managing nausea and vomiting, including those associated with migraines, chemotherapy, and post-operatively.
For treating schizophrenia, psychotic disorders, and managing nausea and vomiting.
Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death.
Outcome:
Increased drowsiness and dizziness
Mechanism:
Additive CNS depression
Outcome:
Decreased absorption of prochlorperazine
Mechanism:
Chelation
Outcome:
Delayed absorption
Mechanism:
Decreased gastric emptying
Most likely new formulation: Extended-release oral formulation (Year: 2026, 70% confidence)
Based on current usage trends and clinical trial activity, there is a low probability (10%) of any major regulatory changes in the next 2 years.
Antipsychotic, Antiemetic
Phenothiazine