Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Cervidil, Cytotec, Hemabate, Prepidil, Prostin E2, Prostin VR Pediatric
Prostaglandins are a group of lipid compounds derived from fatty acids that have diverse hormone-like effects in the body. They act as autocrine or paracrine factors, meaning they affect the cells that produce them or nearby cells, respectively. Prostaglandins are involved in various physiological processes including inflammation, pain, fever, regulation of blood pressure, blood clotting, and reproduction.
Prostaglandins are used to induce labor, terminate pregnancy, treat glaucoma, and maintain patency of the ductus arteriosus in newborns with certain heart defects.
Outcome:
Reduced efficacy of prostaglandins
Mechanism:
NSAIDs inhibit prostaglandin synthesis.
Outcome:
Increased risk of bleeding
Mechanism:
Prostaglandins can inhibit platelet aggregation.
Outcome:
Reduced efficacy of prostaglandins in labor induction.
Mechanism:
Beta-blockers can inhibit uterine contractions.
Most likely new formulation: Controlled-release prostaglandin implants for ophthalmic applications (Year 2026, 60% confidence)
Based on current usage trends and clinical trial activity, there is a 70% likelihood of new prostaglandin analogs being approved for specific indications in the next 5 years.
Eicosanoid, Prostanoid
Eicosanoid