Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Resolor, Motegrity
Prucalopride is a medication used to treat chronic idiopathic constipation (CIC) in adults. It belongs to a class of drugs known as 5-HT4 receptor agonists, which work by stimulating the movement of the gut. This helps to increase the frequency of bowel movements.
For the treatment of chronic idiopathic constipation (CIC) in adults.
Outcome:
Increased prucalopride levels
Mechanism:
Inhibition of CYP3A4 metabolism
Outcome:
Slightly increased prucalopride levels
Mechanism:
Minor inhibition of CYP3A4 metabolism
Outcome:
Slightly decreased prucalopride levels
Mechanism:
Induction of CYP3A4 metabolism
Most likely new formulation: sustained-release formulation (Year 2025, 80% confidence)
Based on current usage trends and clinical trial data, there is a 75% likelihood of expanded indications for prucalopride in other gastrointestinal disorders within the next 5 years.
5-HT4 Receptor Agonist, Prokinetic Agent
Benzamide