Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Accupril
Quinapril is an angiotensin-converting enzyme (ACE) inhibitor primarily used to treat high blood pressure (hypertension) and heart failure. It belongs to a class of drugs that work by widening blood vessels, making it easier for the heart to pump blood. Quinapril is available as a hydrochloride salt and is typically administered orally.
For treating high blood pressure and heart failure.
Fetal toxicity can occur when ACE inhibitors are taken during the second and third trimester of pregnancy. Discontinue quinapril as soon as possible if pregnancy is detected.
Outcome:
Increased risk of hypotension, hyperkalemia, and renal impairment.
Mechanism:
Additive effects on the renin-angiotensin system.
Outcome:
Increased risk of hypotension.
Mechanism:
Additive effects on blood pressure.
Outcome:
Slightly decreased absorption.
Mechanism:
Unknown.
Most likely new formulation: combination therapy with other antihypertensive agents (2025, 70% confidence).
Based on current usage trends and clinical trial data, there is a low likelihood of any major regulatory changes in the next 5 years.
ACE Inhibitor
Nonsulfhydryl-Containing ACE Inhibitor