Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Ranexa
Ranolazine is an antianginal medication used to treat chronic angina. It belongs to a class of drugs known as the late sodium current inhibitors. Ranolazine works by reducing the flow of sodium ions into heart muscle cells, which helps to stabilize the electrical activity of the heart and improve blood flow to the heart muscle during periods of stress or exertion.
For the treatment of chronic angina.
Outcome:
Increased ranolazine levels
Mechanism:
Inhibition of CYP3A4 metabolism
Outcome:
Increased digoxin levels
Mechanism:
Inhibition of P-gp transport
Outcome:
Decreased ranolazine levels
Mechanism:
Induction of CYP3A4 metabolism
Most likely new formulation: Extended-release formulation to improve patient compliance (2025, 60% confidence)
Based on current usage trends and clinical trial data, there is a low likelihood of significant regulatory changes for ranolazine in the next 5 years.
Antianginal Agent, Late Sodium Current Inhibitor
Piperazine Derivative