Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Retin-A, Accutane, Panretin, Targretin, Tazorac, Avita, Renova
Retinoic acid, a derivative of Vitamin A, encompasses a class of compounds with diverse therapeutic uses, primarily in dermatology and oncology. These compounds regulate cell growth and differentiation by binding to specific nuclear receptors. Different retinoids exhibit varying affinities for these receptors, leading to distinct clinical effects. Systemic retinoids are used for severe acne and certain cancers, while topical formulations are common for acne, psoriasis, and photoaging.
Used to treat acne, psoriasis, and certain types of cancer.
For isotretinoin: Causes severe birth defects. Must not be used by patients who are or may become pregnant.
Outcome:
Increased risk of vitamin A toxicity
Mechanism:
Additive effects
Outcome:
Increased risk of dehydration
Mechanism:
Additive effects
Outcome:
Potential for reduced efficacy of both medications
Mechanism:
Oxidation
Most likely new formulation: Combination therapy with retinoids and other dermatological agents (2026, 80% confidence).
Based on current usage trends and clinical trial activity, there is a 70% likelihood of new topical retinoid formulations being approved in the next 5 years.
Retinoid, Vitamin A Derivative
Cyclic Carboxylic Acid