Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Edurant
Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults. It works by blocking the reverse transcriptase enzyme, which HIV needs to replicate its genetic material. This prevents the virus from multiplying and spreading throughout the body.
For the treatment of HIV-1 infection in combination with other antiretroviral agents.
Outcome:
Decreased rilpivirine levels
Mechanism:
Induction of CYP3A4 enzymes
Outcome:
Decreased rilpivirine absorption
Mechanism:
Chelation or altered gastric pH
Outcome:
No clinically significant interaction
Mechanism:
Not applicable
Most likely new formulation: Long-acting injectable rilpivirine (2025, 70% confidence)
Based on current usage trends and clinical trial data, there is a high likelihood (85%) of rilpivirine maintaining its approved status for HIV-1 treatment.
Antiretroviral, Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI)
Diarylpryrimidine