Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Maxalt, Rizalt, Rizatriptan Teva
Rizatriptan is a selective serotonin (5-HT1B/1D) receptor agonist used to treat migraine headaches. It belongs to the triptan class of drugs, which are specifically designed to target serotonin receptors involved in migraine pathophysiology. Rizatriptan constricts blood vessels in the brain, reducing inflammation and pain associated with migraine attacks. It does not prevent migraines or reduce the frequency of attacks, but it can alleviate symptoms once they begin.
For the acute treatment of migraine headaches with or without aura.
Outcome:
Serotonin syndrome
Mechanism:
Increased serotonin levels
Outcome:
Increased rizatriptan levels
Mechanism:
Inhibition of rizatriptan metabolism
Outcome:
Enhanced antimigraine effect
Mechanism:
Synergistic effect
Most likely new formulation: Quick-dissolving oral film (Year: 2025, 70% confidence)
Based on current usage trends and clinical trial data, there is a low likelihood of any major regulatory changes for rizatriptan in the next 5 years (less than 5% probability).
Serotonin receptor agonist, Triptan, Antimigraine
Selective 5-HT1B/1D receptor agonist