Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Crestor, Rosuvas, Rovastatin, Rosucard, Vizarsin, Teva-Rosuvastatin, Apo-Rosuvastatin, Sandoz Rosuvastatin, Ranbaxy Rosuvastatin
Rosuvastatin is a member of the drug class known as statins, specifically HMG-CoA reductase inhibitors. It is primarily used to lower cholesterol and reduce the risk of cardiovascular events like heart attack and stroke. Rosuvastatin works by inhibiting the enzyme HMG-CoA reductase, which plays a crucial role in the production of cholesterol in the liver. This leads to a decrease in the levels of LDL (bad) cholesterol, total cholesterol, and triglycerides, while increasing HDL (good) cholesterol.
For lowering cholesterol and reducing the risk of cardiovascular events.
Outcome:
Increased rosuvastatin levels
Mechanism:
Inhibition of metabolism
Outcome:
Additive cholesterol-lowering effect
Mechanism:
Different mechanisms of action
Outcome:
Increased rosuvastatin levels
Mechanism:
CYP3A4 inhibition
Most likely new formulation: controlled-release rosuvastatin (2025, 75% confidence)
Based on current usage trends and clinical trial data, there is a 90% likelihood that rosuvastatin will remain a first-line therapy for hypercholesterolemia for the next 5 years.
HMG-CoA Reductase Inhibitor, Statin
Pyrimidine/Dihydro-Pyrimidine/Pyrimidinedione