Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Banzel, Inomitol
Rufinamide is an anticonvulsant medication used as adjunctive therapy for seizures associated with Lennox-Gastaut syndrome, a severe form of epilepsy. It belongs to the triazole class of antiepileptic drugs and is believed to work by modulating the activity of sodium channels in the brain, thereby stabilizing neuronal membranes and reducing the likelihood of seizures.
Used as adjunctive therapy for seizures associated with Lennox-Gastaut syndrome.
Outcome:
Decreased rufinamide levels
Mechanism:
Enzyme induction
Outcome:
Potential for decreased efficacy of both drugs
Mechanism:
Pharmacokinetic interaction
Outcome:
Rufinamide may decrease efficacy of oral contraceptives
Mechanism:
Enzyme induction
Most likely new formulation: Extended-release formulation (Year 2026, 65% confidence)
Based on current usage trends and clinical trial data, there is a 70% likelihood of rufinamide maintaining its current FDA approval status for Lennox-Gastaut Syndrome over the next 5 years.
Anticonvulsant, Antiepileptic
Triazole