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Brand: Sucraid
Sacrosidase is an enzyme replacement therapy used to manage Congenital Sucrase-Isomaltase Deficiency (CSID), a rare genetic disorder. Individuals with CSID lack the enzyme sucrase-isomaltase, which is essential for breaking down sucrose (table sugar) and some starches into simpler sugars like glucose and fructose. Without this enzyme, consuming these sugars can lead to gastrointestinal symptoms like diarrhea, bloating, and abdominal pain. Sacrosidase works by providing the missing enzyme, allowing individuals with CSID to better tolerate these sugars in their diet.
For the management of Congenital Sucrase-Isomaltase Deficiency (CSID).
Outcome:
Symptoms if Sacrosidase is inadequate.
Mechanism:
Insufficient enzyme to break down sucrose
Outcome:
Reduced efficacy of sacrosidase
Mechanism:
Acarbose inhibits alpha-glucosidase, which can interfere with sacrosidase's activity.
Outcome:
Potentially reduced efficacy of sacrosidase
Mechanism:
Altered gastric pH may impact sacrosidase activity.
Potential future innovations may involve improved enzyme formulations with enhanced stability or targeted delivery mechanisms (50% confidence by 2028).
Given the rarity of CSID and the established efficacy of sacrosidase, the regulatory landscape is likely to remain stable.
Enzyme Replacement Therapy
Glycoside Hydrolase