Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Disalcid, Salsitab
Salsalate is a non-acetylated salicylate, a type of non-steroidal anti-inflammatory drug (NSAID). It works by inhibiting the production of prostaglandins, chemicals in the body that cause pain, fever, and inflammation. Unlike aspirin, salsalate does not inhibit platelet aggregation, making it a suitable option for patients with bleeding disorders or those taking anticoagulants.
For relief of pain, fever, and inflammation associated with osteoarthritis, rheumatoid arthritis, and other musculoskeletal conditions.
Outcome:
Increased bleeding risk
Mechanism:
Salsalate can displace warfarin from protein binding sites, increasing its free concentration.
Outcome:
Enhanced hypoglycemic effects
Mechanism:
May potentiate the effects of sulfonylureas.
Outcome:
Reduced salsalate absorption
Mechanism:
Antacids can alter the pH of the stomach, affecting salsalate absorption.
Most likely new formulation: Extended-release formulation for improved patient compliance (2025, 70% confidence).
Based on current usage trends and safety profile, salsalate is expected to maintain its approved status for the foreseeable future (95% confidence).
Nonsteroidal Anti-Inflammatory Drug (NSAID), Salicylate
Salicylate