Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Invirase, Fortovase
Saquinavir is an antiretroviral medication used in combination with other medications to treat human immunodeficiency virus (HIV) infection. It belongs to a class of drugs called protease inhibitors, which work by blocking the action of HIV protease, an enzyme that is essential for the virus to replicate. Saquinavir helps to reduce the amount of HIV in the body, improving immune function and slowing the progression of HIV disease.
For the treatment of HIV infection in combination with other antiretroviral medications.
Outcome:
Reduced saquinavir levels
Mechanism:
Induction of CYP3A4
Outcome:
Increased saquinavir levels
Mechanism:
Inhibition of CYP3A4
Outcome:
No clinically significant interaction
Mechanism:
Unknown
Most likely new formulation: Long-acting injectable formulation (2025, 70% confidence)
Based on current usage trends and clinical trial data, saquinavir is likely to remain a valuable component of HIV treatment regimens.
Antiretroviral, Protease Inhibitor
Hydroxyethylamine