Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Anectine, Quelicin
Succinylcholine is a depolarizing neuromuscular blocking agent used as a skeletal muscle relaxant during surgery and other procedures. It works by mimicking the action of acetylcholine, initially causing muscle contraction (fasciculations) followed by paralysis. It is classified as a nicotinic acetylcholine receptor agonist.
Used as a muscle relaxant during surgery, intubation, and other medical procedures requiring skeletal muscle paralysis.
Succinylcholine can cause malignant hyperthermia, a life-threatening condition characterized by a rapid rise in body temperature and severe muscle contractions. Appropriate treatment for malignant hyperthermia should be readily available.
Outcome:
Increased neuromuscular blockade
Mechanism:
Synergistic effect at the neuromuscular junction
Outcome:
Enhanced neuromuscular blockade
Mechanism:
Pre- and post-junctional effects
Outcome:
Minimal clinically significant interaction
Mechanism:
None well established
Most likely new formulation: Ultra-short-acting succinylcholine analog (Year: 2028, 70% confidence)
Based on current usage trends and safety profile, the likelihood of succinylcholine remaining a first-line agent for rapid sequence intubation is 85%.
Neuromuscular Blocking Agent, Depolarizing Agent
Dicholine Ester of Succinic Acid