Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Lamisil, Terbinex, Sebifin, Zabel
Terbinafine is an antifungal medication used to treat fungal infections of the skin, hair, and nails. It belongs to the class of allylamines and works by inhibiting the enzyme squalene epoxidase, which is essential for fungal cell wall synthesis. This leads to the accumulation of squalene and ultimately fungal cell death.
For treatment of fungal infections of the skin, hair, and nails, including athlete's foot, ringworm, jock itch, and onychomycosis.
Outcome:
Decreased terbinafine levels
Mechanism:
Induction of CYP450 enzymes
Outcome:
Increased caffeine levels
Mechanism:
Inhibition of CYP1A2
Outcome:
Decreased terbinafine absorption
Mechanism:
Reduced gastric acidity
Most likely new formulation: Topical nanoparticle delivery system (Year 2025, 75% confidence)
Based on current usage trends and clinical trial data, there is a 90% likelihood that terbinafine will maintain its approved status for the treatment of fungal infections.
Antifungal
Allylamines