Medicines
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Discover all available medicines and treatments
Brand: Glypressin, Variquel
Terlipressin is a synthetic analog of vasopressin, an antidiuretic hormone. It acts as a vasoconstrictor, primarily affecting the splanchnic circulation, and is used to manage bleeding from esophageal varices and hepatorenal syndrome. It belongs to the class of vasoconstrictors and has a selective effect on V1 receptors.
For controlling bleeding from esophageal varices, managing hepatorenal syndrome, and sometimes used in septic shock.
Outcome:
Increased risk of hyponatremia
Mechanism:
Synergistic effect on water retention
Outcome:
Reduced effectiveness of terlipressin
Mechanism:
Counteracting effects on fluid balance
Outcome:
Delayed absorption
Mechanism:
Altered gastric emptying
Most likely new formulation: sustained-release terlipressin for improved patient compliance (Year: 2026, 80% confidence).
Based on current usage trends and clinical trial data, there is a 70% likelihood of terlipressin expanding its indications to include other forms of gastrointestinal bleeding within the next 5 years.
Vasoconstrictor, Antidiuretic Hormone Analog
Peptide Hormone Analog