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Brand: Myoview
Tetrofosmin is a cationic myocardial perfusion imaging agent used in conjunction with technetium-99m (99mTc) to assess blood flow to the heart muscle. It is used in diagnostic nuclear medicine procedures, such as single-photon emission computed tomography (SPECT), to help detect and evaluate coronary artery disease. Tetrofosmin is taken up by the myocardium proportionally to blood flow and allows visualization of areas with reduced perfusion, indicating potential blockages or narrowing of the coronary arteries.
Used for myocardial perfusion imaging to assess blood flow to the heart muscle and evaluate coronary artery disease.
Outcome:
Reduced tetrofosmin uptake
Mechanism:
Competition for cellular uptake mechanisms.
Outcome:
May affect myocardial perfusion
Mechanism:
Caffeine's effects on blood flow.
Outcome:
Potential for reduced absorption of tetrofosmin.
Mechanism:
Chelation or altered gastric pH.
Most likely new formulation or application: Technetium-99m generator shortages may drive research into alternative radioisotopes for myocardial perfusion imaging (2025, 60% confidence).
Based on current usage trends and clinical trial activity, there is a low ( <5%) likelihood of major regulatory changes for tetrofosmin in the next 2 years.
Diagnostic Imaging Agent, Myocardial Perfusion Agent
Diphosphine