Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Gabitril
Tiagabine is an anticonvulsant medication used to treat partial-onset seizures in adults and children 12 years and older. It belongs to a class of drugs called selective GABA reuptake inhibitors, which work by increasing the levels of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits nerve activity in the brain.
For the adjunctive treatment of partial-onset seizures in adults and children 12 years and older.
Outcome:
Increased sedation and dizziness
Mechanism:
Additive CNS depressant effects
Outcome:
Increased risk of seizures
Mechanism:
Pharmacodynamic interaction
Outcome:
May decrease effectiveness of oral contraceptives
Mechanism:
Induction of hepatic enzymes
Most likely new formulation: Extended-release formulation (Year: 2025, 30% confidence)
Based on current usage trends and clinical trial data, there is a low probability (<5%) of any major regulatory changes for tiagabine in the next 2 years.
Anticonvulsant, GABA Reuptake Inhibitor
Nipecotic Acid Derivative