Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Livial, TIBOLONE Teva, Tibofem, Livial Comfort
Tibolone is a synthetic steroid medication used in menopausal hormone therapy to alleviate vasomotor symptoms (such as hot flashes and night sweats) and to prevent osteoporosis. It has estrogenic, progestogenic, and androgenic effects, acting as a tissue-selective estrogen complex (TSEC). This means it acts differently in various tissues, providing benefits similar to hormone replacement therapy (HRT) with potentially fewer risks.
For the relief of menopausal symptoms and prevention of osteoporosis in postmenopausal women.
Outcome:
Reduced effectiveness of tibolone
Mechanism:
Enzyme induction
Outcome:
Potential for increased side effects
Mechanism:
Altered metabolism
Outcome:
Potential for increased anxiety or insomnia
Mechanism:
Additive stimulant effect
Most likely new formulation: Transdermal patch (Year 2025, 70% confidence)
Based on current usage trends and clinical trial data, there is a 90% likelihood of tibolone remaining a prescribed medication for menopausal symptoms.
Synthetic Steroid, Selective Estrogen Receptor Modulator (SERM)
Steroid