Medicines
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Discover all available medicines and treatments
Brand: Thiola
Tiopronin is a thiol-containing drug primarily used to prevent cystine stones in patients with cystinuria. It acts by reducing cystine levels in the urine, making it less likely to form stones. It is classified as a mucolytic agent and belongs to the aminothiol class.
For prevention of cystine stones in patients with cystinuria.
Outcome:
Increased risk of nephrotoxicity
Mechanism:
Additive renal toxicity
Outcome:
Decreased effectiveness of tiopronin
Mechanism:
May interfere with cystine reduction
Outcome:
Potential decreased absorption of tiopronin
Mechanism:
May contain chelating agents
Most likely new formulation: Extended-release formulation (Year: 2026, 70% confidence)
Based on current usage and safety data, the likelihood of tiopronin remaining on the market with its current indication is high (95%).
Mucolytic, Antiurolithic
Aminothiol