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Generic: Thallium chloride, Thallous chloride
Thallium(I) chloride (TlCl) is a highly toxic inorganic compound. Historically, it had limited medical use as a topical treatment for ringworm and other skin infections, but its toxicity led to its discontinuation. TlCl also finds applications in scientific research, particularly in infrared optics and as a scintillator in radiation detectors. Due to its toxicity, handling requires extreme caution.
Previously used topically for certain skin infections, now primarily used in scientific research.
Thallium(I) chloride is highly toxic and can cause severe adverse effects, including death. Exposure can occur through ingestion, inhalation, or skin contact. Symptoms of thallium poisoning include hair loss, gastrointestinal disturbances, neurological damage, and cardiovascular effects.
Outcome:
Altered potassium levels, potentially leading to cardiac arrhythmias.
Mechanism:
Tl+ competes with K+ for binding sites in the body.
Outcome:
Increased or decreased efficacy of chelating agents.
Mechanism:
Competition for thallium binding.
Outcome:
Potential competition for absorption.
Mechanism:
Competition for binding sites in the gut.
Research on less toxic thallium compounds for niche applications in imaging or diagnostics is possible but with low probability (5% confidence by 2030).
Due to its high toxicity and limited therapeutic benefit, TlCl is unlikely to be re-approved for any medical use.
Heavy Metal Salt, Inorganic Compound
Metal Halide