Medicines
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Discover all available medicines and treatments
Brand: Topamax, Trokendi XR, Qudexy XR, Topiragen, Topiramate Accord, Topiramate Mylan, Topiramate Sandoz
Topiramate is an anticonvulsant medication used to treat epilepsy and prevent migraine headaches. It is classified as a sulfamate-substituted monosaccharide and works by affecting multiple neurotransmitter systems in the brain, including GABA, glutamate, and sodium channels.
For the treatment of epilepsy and prevention of migraine headaches.
May cause fetal harm when administered to a pregnant woman. Can cause decreased sweating and increased body temperature (especially in children).
Outcome:
Increased drowsiness and dizziness
Mechanism:
Additive CNS depressant effects
Outcome:
Reduced digoxin levels
Mechanism:
Unknown
Outcome:
Reduced absorption of topiramate
Mechanism:
Unknown
Most likely new formulation: Extended-release formulation for improved patient compliance (Year: 2025, 60% confidence)
Based on current usage trends and clinical trial outcomes, there is a 75% likelihood of topiramate maintaining its current FDA approval status for epilepsy and migraine prevention over the next 5 years.
Anticonvulsant, Antiepileptic, Migraine Prophylactic
Sulfamate-substituted monosaccharide