Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Fareston
Toremifene is a nonsteroidal selective estrogen receptor modulator (SERM) primarily used to treat metastatic breast cancer in postmenopausal women. It acts as an estrogen antagonist in breast tissue, blocking the growth-promoting effects of estrogen on some breast cancers. It can also have estrogenic effects in other tissues like bone, helping to maintain bone density.
Treatment of metastatic breast cancer in postmenopausal women.
Increased risk of endometrial cancer, stroke, and pulmonary embolism.
Outcome:
Increased bleeding risk
Mechanism:
Altered metabolism
Outcome:
Reduced absorption of toremifene
Mechanism:
Chelation
Outcome:
Potential for increased liver toxicity
Mechanism:
Additive liver stress
Most likely new formulation: Extended-release formulation (Year: 2026, 60% confidence)
Based on current usage trends and clinical trial data, there is a low likelihood of significant regulatory changes in the near future.
Selective Estrogen Receptor Modulator (SERM), Antineoplastic
Triphenylethylene Derivative