Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Ultram, ConZip, Ryzolt, Qdolo
Tramadol is a synthetic opioid analgesic used to treat moderate to moderately severe pain. It acts on the opioid receptors in the central nervous system, altering the perception and response to pain. Tramadol also inhibits the reuptake of norepinephrine and serotonin, contributing to its analgesic effects.
For the management of moderate to moderately severe pain.
Tramadol is associated with risks of addiction, abuse, and misuse, which can lead to overdose and death. Respiratory depression and seizures are also risks.
Outcome:
Increased sedation, respiratory depression
Mechanism:
Additive CNS depressant effects
Outcome:
Serotonin Syndrome
Mechanism:
Increased serotonin levels
Outcome:
Potential altered INR
Mechanism:
Unknown
Most likely new formulation: extended-release combination with a non-opioid analgesic (2025, 70% confidence)
Based on current usage trends and emerging alternatives, there is a 15% likelihood of stricter regulatory controls on tramadol prescriptions within the next 5 years.
Opioid Analgesic, Centrally Acting
Cyclohexanol derivative