Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Mavik, Tarka
Trandolapril is an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure (hypertension). It belongs to a class of drugs that work by relaxing blood vessels, allowing blood to flow more easily and reducing the workload on the heart. Trandolapril is often prescribed alone or in combination with other antihypertensive medications.
For treating high blood pressure (hypertension), often in combination with other medications.
Fetal toxicity: Can cause injury and even death to the developing fetus when used during the second and third trimesters of pregnancy.
Outcome:
Hyperkalemia
Mechanism:
Reduced potassium excretion
Outcome:
Increased risk of hypotension
Mechanism:
Additive hypotensive effects
Outcome:
Slightly reduced trandolapril absorption
Mechanism:
Unknown
Most likely new formulation: Combination therapy with other antihypertensives (2024, 70% confidence)
Based on current usage trends and clinical trial data, there is a low ( <5%) likelihood of any major regulatory changes for trandolapril in the next 2 years.
ACE Inhibitor, Antihypertensive
Non-sulfhydryl-containing ACE inhibitor