Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Kenalog, Aristocort, Nasacort, Azmacort, Triderm, Tri-Nasal
Triamcinolone is a synthetic corticosteroid used to treat various inflammatory and allergic conditions. It is a potent glucocorticoid with anti-inflammatory, immunosuppressive, and anti-allergic properties. Triamcinolone works by binding to glucocorticoid receptors in the cytoplasm, translocating to the nucleus, and modulating gene expression. This leads to decreased production of inflammatory mediators and suppression of the immune response.
For the treatment of inflammatory and allergic conditions such as skin disorders, asthma, allergies, and certain autoimmune diseases.
Outcome:
Increased risk of gastrointestinal bleeding
Mechanism:
Synergistic effect on platelet inhibition
Outcome:
Increased risk of gastrointestinal ulcers
Mechanism:
Additive effect on gastric mucosa irritation
Outcome:
Decreased triamcinolone absorption
Mechanism:
Binding of triamcinolone in the gastrointestinal tract
Most likely new formulation: Extended-release injectable (Year: 2025, 60% confidence)
Based on current usage trends and ongoing clinical trials, there is a 70% likelihood of triamcinolone maintaining its current regulatory status for the next 5 years.
Corticosteroid, Glucocorticoid
Glucocorticoid