Medicines
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Discover all available medicines and treatments
Brand: Tigan
Trimethobenzamide is an antiemetic drug used to treat nausea and vomiting. It belongs to the class of antihistamines and works by blocking dopamine and serotonin receptors in the chemoreceptor trigger zone (CTZ) of the brain, which is responsible for inducing vomiting. It's available in various forms, including capsules, tablets, and suppositories.
For the treatment of nausea and vomiting associated with various conditions, including gastroenteritis, motion sickness, and post-operative nausea.
Outcome:
Increased drowsiness and sedation.
Mechanism:
Additive CNS depressant effects.
Outcome:
Increased drowsiness.
Mechanism:
Additive antihistamine effects.
Outcome:
May delay absorption.
Mechanism:
Delayed gastric emptying.
Most likely new formulation: Extended-release formulation for improved patient compliance (Year: 2026, 30% confidence)
Based on current usage patterns and clinical trial data, there is a low ( <5%) likelihood of regulatory changes affecting trimethobenzamide's status in the next 5 years.
Antiemetic, Antihistamine
Benzamide