Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Rezulin
Troglitazone, a thiazolidinedione (TZD), was an oral antidiabetic drug used to treat type 2 diabetes. It worked by improving insulin sensitivity. However, it was withdrawn from the market due to severe hepatotoxicity.
Used to treat type 2 diabetes by improving insulin sensitivity.
Outcome:
Reduced troglitazone absorption
Mechanism:
Binding interaction
Outcome:
Additive effects on glucose lowering
Mechanism:
Different mechanisms of action
Outcome:
May slightly decrease troglitazone effectiveness
Mechanism:
Unknown
No new formulations of troglitazone are expected due to its safety profile.
Due to its withdrawal, there is a 0% likelihood of troglitazone being reintroduced to the market.
Antidiabetic, Thiazolidinedione
Thiazolidinedione