Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Sanctura, Sanctura XR, Regurin, Spasmex, Urillac
Trospium is an anticholinergic medication primarily used to treat overactive bladder (OAB). It works by blocking the action of acetylcholine, a neurotransmitter that stimulates muscle contractions in the bladder. This helps to reduce urinary urgency, frequency, and incontinence. It belongs to a class of drugs known as antimuscarinics or antispasmodics. Trospium is available in both immediate-release and extended-release formulations.
For the treatment of overactive bladder (OAB) symptoms, such as urinary urgency, frequency, and urge incontinence.
Outcome:
Increased risk of gastrointestinal ulcers or bleeding
Mechanism:
Additive anticholinergic effects
Outcome:
Increased digoxin levels
Mechanism:
Reduced gastrointestinal motility may enhance digoxin absorption.
Outcome:
Potential for slightly increased trospium levels
Mechanism:
Inhibition of CYP3A4 enzyme.
Most likely new formulation: Transdermal patch (2025, 75% confidence)
Based on current usage trends and clinical trial data, there is a 90% likelihood of trospium remaining a first-line treatment for OAB in the next 5 years.
Anticholinergic, Antimuscarinic
Quaternary Ammonium Compound