Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: ella, Esmya, Fibristal
Ulipristal acetate is a selective progesterone receptor modulator (SPRM) used primarily for emergency contraception and the treatment of uterine fibroids. It works by blocking the effects of progesterone, a hormone that plays a crucial role in the menstrual cycle and pregnancy. In emergency contraception, it prevents or delays ovulation. For fibroids, it reduces their size and associated symptoms like heavy bleeding.
Used for emergency contraception and treatment of uterine fibroids.
Serious liver injury has been reported. Ulipristal acetate should not be used in women with known or suspected liver disease.
Outcome:
Reduced effectiveness of ulipristal
Mechanism:
Induction of hepatic enzymes
Outcome:
Reduced effectiveness of ulipristal
Mechanism:
Hormonal antagonism
Outcome:
No clinically significant interaction expected
Mechanism:
None known
Most likely new formulation: Extended-release for fibroid treatment (Year 2026, 60% confidence)
Based on current usage trends and safety profile, there is a 70% likelihood of continued approval for existing indications.
Selective Progesterone Receptor Modulator (SPRM)
Synthetic Steroid