Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Generic: VACV
VACV, short for Vaccinia virus, is a large, complex, enveloped virus belonging to the Poxviridae family. It is most notably known for its role in the eradication of smallpox, a devastating human disease. VACV is used as a vector in vaccine development and gene therapy due to its ability to infect a wide range of host cells and its large genome that can accommodate foreign genetic material. It has also been studied as an oncolytic virus, showing potential in treating certain types of cancer.
Used in vaccine development, gene therapy, and studied as a potential oncolytic virus for cancer treatment.
Outcome:
Reduced efficacy of VACV-based therapies
Mechanism:
Suppression of immune response required for viral activity
Outcome:
Potential masking of inflammatory response to VACV
Mechanism:
Inhibition of prostaglandin synthesis
Outcome:
Potential reduced absorption of some medications administered orally
Mechanism:
Changes in gastric pH
Most likely new formulation: Enhanced tumor targeting through genetic modification (Year: 2025, 80% confidence)
Based on current research and clinical trial progress, there is a 70% likelihood of FDA approval for at least one VACV-based oncolytic virus within the next 5 years.
Live Attenuated Virus, Poxvirus
Virus