Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Chantix, Champix
Varenicline is a prescription medication used to help adults quit smoking. It is a nicotinic receptor partial agonist, meaning it binds to the same receptors in the brain as nicotine but stimulates them less intensely, reducing cravings and withdrawal symptoms. It also blocks the rewarding effects of nicotine from cigarettes, making smoking less pleasurable.
For smoking cessation in adults.
Outcome:
Increased risk of neuropsychiatric symptoms
Mechanism:
Pharmacodynamic interaction
Outcome:
May enhance caffeine effects
Mechanism:
Pharmacokinetic interaction
Outcome:
May slightly decrease varenicline absorption
Mechanism:
Pharmacokinetic interaction
Most likely new formulation: Extended-release formulation for improved adherence (Year: 2026, 70% confidence)
Based on usage patterns and clinical trial data, there is a low probability (5%) of any new black box warnings being issued in the next 5 years.
Smoking Cessation Aid
Pyridine derivative