Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Vfend
Voriconazole is a triazole antifungal medication used to treat a variety of serious fungal infections. It works by inhibiting the synthesis of ergosterol, a crucial component of fungal cell membranes. This disruption leads to increased cell membrane permeability and ultimately fungal cell death. Voriconazole is typically reserved for severe infections due to its potential for serious side effects.
For the treatment of serious fungal infections such as invasive aspergillosis, candidiasis, and other life-threatening mycoses.
Voriconazole can cause serious side effects, including visual disturbances, liver damage, and skin reactions. Patients should be monitored closely for these effects.
Outcome:
Reduced voriconazole levels
Mechanism:
CYP450 induction
Outcome:
Increased tacrolimus levels
Mechanism:
CYP3A4 inhibition
Outcome:
Slightly reduced voriconazole absorption
Mechanism:
Gastric pH alteration
Most likely new formulation: Extended-release oral formulation (Year 2025, 80% confidence)
Based on current usage trends and emerging resistance patterns, there is a 70% likelihood of increased restrictions on voriconazole use in the next 5 years.
Antifungal, Triazole
Triazole