Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Coumadin, Jantoven
Warfarin is an anticoagulant medication used to prevent and treat blood clots. It belongs to the class of drugs known as coumarins and works by inhibiting the synthesis of vitamin K-dependent clotting factors in the liver. It's crucial for managing conditions like deep vein thrombosis, pulmonary embolism, and preventing stroke in patients with atrial fibrillation or artificial heart valves.
For preventing and treating blood clots in conditions like deep vein thrombosis, pulmonary embolism, and to prevent stroke in patients with atrial fibrillation or artificial heart valves.
Warfarin can cause major or fatal bleeding. Regular monitoring of the international normalized ratio (INR) is required. Patients should be carefully instructed about factors that can alter INR.
Outcome:
Increased risk of bleeding
Mechanism:
Synergistic effects on platelet function and coagulation cascade.
Outcome:
Altered INR
Mechanism:
Effects on gut flora that synthesize vitamin K.
Outcome:
Decreased INR
Mechanism:
High vitamin K content can counteract warfarin's effects.
Most likely new formulation: extended-release warfarin (Year 2026, 70% confidence)
Based on usage patterns and adverse event reports, there is a 2% likelihood of new safety warnings related to bleeding risk being issued within the next 5 years.
Anticoagulant
Coumarin