Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Zyprexa, Zyprexa Zydis, Zaponex
Zyprexa, generically known as olanzapine, is an atypical antipsychotic medication primarily used to treat schizophrenia and bipolar disorder. It works by affecting the balance of certain chemicals in the brain, specifically dopamine and serotonin. Olanzapine belongs to the thienobenzodiazepine class and is available in various forms, including tablets, orally disintegrating tablets, and short-acting injections.
For the treatment of schizophrenia and bipolar disorder.
Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. ZYPREXA is not approved for the treatment of patients with dementia-related psychosis.
Outcome:
Increased sedation and dizziness
Mechanism:
Additive CNS depressant effects
Outcome:
Slightly increased olanzapine levels
Mechanism:
Weak inhibition of CYP1A2
Outcome:
May slightly decrease olanzapine levels
Mechanism:
CYP1A2 induction
Most likely new formulation: Long-acting injectable olanzapine (2025, 75% confidence)
Based on usage trends and clinical trial data, there is a 90% likelihood that olanzapine will maintain its current FDA approval status for the next 5 years.
Atypical Antipsychotic
Thienobenzodiazepine