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Prof. Dr. at Chemistry
Ask questions about Ayşegül Karaküçük‐İyidoğan's research, publications, and ongoing work
Developed novel platinum(II) and palladium(II) complexes of thiosemicarbazones and investigated their antiviral and cytotoxic activities, contributing to the development of potential therapeutic agents.
Synthesized and evaluated new piperidine-hydrazone derivatives as acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors, with molecular docking studies to understand their mechanism of action.
Synthesized and evaluated novel chiral thiosemicarbazone derivatives for anticancer activity, including structural elucidation and in silico studies to understand their mechanism of action.
Synthesized and evaluated novel chalcones bearing morpholine moiety as antiproliferative agents, contributing to the discovery of potential anticancer agents.
Designed and synthesized novel pyrrolidine-based chalcones as dual inhibitors of α-amylase and α-glucosidase, with molecular docking and ADMET profiling, and pharmacological screening.
Synthesized and evaluated the anticancer activity of new hydrazide-hydrazones and their Pd(II) complexes, contributing to the development of potential anticancer agents.
Synthesized and characterized pyrazolo derivatives and investigated their antioxidant and anticholinesterase activities.
Professor Ayşegül Karaküçük-İyidoğan is a leading researcher in the synthesis and biological evaluation of novel heterocyclic compounds, with a focus on their potential as anticancer, antiviral, and antioxidant agents. Her work integrates chemical synthesis, structural elucidation, and in silico studies to discover and develop new pharmaceuticals.
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