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Researcher at Research Department
Ask questions about Chunhong Jiang's research, publications, and ongoing work
Demonstrated that Andrographolide inhibits AIM2 inflammasome-mediated pyroptosis, contributing to the amelioration of radiation-induced lung inflammation and fibrosis.
Showed that Andrographolide alleviates Parkinsonism in MPTP-PD mice by targeting mitochondrial fission mediated by dynamin-related protein 1.
Demonstrated that Andrographolide sulfonate ameliorates lipopolysaccharide-induced acute lung injury in mice by down-regulating MAPK and NF-κB pathways.
Showed that Andrographolide sulfonate improves Alzheimer-associated phenotypes and mitochondrial dysfunction in APP/PS1 transgenic mice.
Found that Andrographolide potentiates PD-1 blockade immunotherapy by inhibiting COX2-mediated PGE2 release.
Provided insights into the biosynthesis of the bioactive diterpenoid neoandrographolide through the genome of the medicinal plant Andrographis paniculata.
Dr. Chunhong Jiang's research focuses on the therapeutic potential of natural compounds, particularly andrographolide, and their application in treating various diseases, including lung inflammation, Parkinson's disease, and Alzheimer's disease. Her work also explores the use of AI and machine learning in biomedical applications.
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