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Researcher at Research Department
Ask questions about Hai‐Liang Zhu's research, publications, and ongoing work
Synthesized and characterized 1,3,4-Thiadiazole derivatives, exploring their applications in medicinal, agricultural, and materials chemistry, demonstrating broad utility in various fields.
Synthesized and evaluated Schiff bases derived from 5-chloro-salicylaldehyde, demonstrating significant antimicrobial activity and potential for development as novel antibiotics.
Synthesized and biologically evaluated pyrazole derivatives containing a thiourea skeleton, demonstrating their potential as anticancer agents through in vitro and in vivo studies.
Created fluorescent sensors for the detection of hydrazine in environmental and biological systems, offering improved sensitivity and selectivity for hydrazine detection.
Investigated urea derivatives as anticancer agents, elucidating their mechanisms of action and potential for clinical application in cancer therapy.
Developed small-molecule fluorescent probes for the detection of hydrogen peroxide, enabling real-time monitoring of oxidative stress in biological systems.
Synthesized and characterized Schiff base metal complexes, demonstrating their inhibitory activities against urease and potential for treating Helicobacter pylori infections.
Designed and synthesized a near-infrared fluorescent probe for imaging dynamic peroxynitrite fluxes in epileptic brains, providing insights into the role of peroxynitrite in epilepsy.
Hai-Liang Zhu is a distinguished researcher at Nanjing University, specializing in medicinal chemistry and chemical biology, with a focus on the design, synthesis, and biological evaluation of novel therapeutic agents, particularly for cancer and infectious diseases. His work emphasizes the development of fluorescent probes for biomedical applications and the study of enzyme inhibitors.
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