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Hailun Jiang
Researcher at Research Department
Acupuncture Treatment Research Studies
Alzheimer'S Disease Research And Treatments
Cholinesterase And Neurodegenerative Diseases
Microrna In Disease Regulation
Neurological Disease Mechanisms And Treatments
1.1K
Citations
20
H-index
0
Patents
76
Publications
0
Grants
$0
Total Funding
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Research Contributions
Investigated the effects of Luteolin on inflammation in a human blood-brain barrier model.
Demonstrated that Luteolin inhibits fibrillary β-Amyloid1–40-induced inflammation in a human blood-brain barrier model by suppressing the p38 MAPK-mediated NF-κB signaling pathways.
Molecules (2017)
Explored the role of miR-200a-3p in Alzheimer's disease.
Showed that MicroRNA-200a-3p mediates neuroprotection in Alzheimer-related deficits and attenuates Amyloid-Beta overproduction and Tau hyperphosphorylation via coregulating BACE1 and PRKACB.
Frontiers in Pharmacology (2019)
Studied the impact of acupuncture treatment on post-stroke cognitive impairment.
Examined the effect of acupuncture treatment on post-stroke cognitive impairment, contributing to the understanding of non-pharmacological interventions.
Medicine (2020)
Analyzed the effects of miR-23b-3p on cognition in Alzheimer's disease.
Demonstrated that miR-23b-3p rescues cognition in Alzheimer’s disease by reducing tau phosphorylation and apoptosis via GSK-3β signaling pathways.
Molecular Therapy — Nucleic Acids (2022)
Investigated the role of miR-148a-3p signaling in Alzheimer's disease.
Examined the implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer’s disease.
Molecular Therapy — Nucleic Acids (2021)
Explored the therapeutic potential of Tilianin in ischemic injury.
Showed that Tilianin mediates neuroprotection against ischemic injury by attenuating CaMKII-dependent mitochondrion-mediated apoptosis and MAPK/NF-κB signaling.
Life Sciences (2018)
Examined the effects of acupuncture on post-stroke depression.
Investigated the role of intestinal microbiota in the effects of acupuncture treatment for post-stroke depression.
Frontiers in Neuroscience (2023)
Studied the impact of Vitegnoside on neuronal injury in an Alzheimer's disease cell model.
Demonstrated that Vitegnoside mitigates neuronal injury, mitochondrial apoptosis, and inflammation in an Alzheimer’s Disease cell model via the p38 MAPK/JNK Pathway.
Journal of Alzheimer s Disease (2019)
Investigated the effects of total flavonoid extract from Dracocephalum moldavica L. on beta-amyloid-induced toxicity.
Showed that total flavonoid extract from Dracocephalum moldavica L. attenuates β-amyloid-induced toxicity through anti-amyloidogenesic and neurotrophic pathways.
Life Sciences (2017)
Studied the use of acupuncture for insomnia in hypertensive patients.
Conducted a systematic review and meta-analysis on the use of acupuncture for insomnia symptoms in hypertensive patients.
Frontiers in Neurology (2024)
Research Highlights
Dr. Hailun Jiang is a researcher at Beijing Tiantan Hospital specializing in neurological disorders and the application of traditional Chinese medicine, particularly acupuncture, for stroke and other neurological conditions. Her work focuses on microRNA, signaling pathways, and the development of novel therapeutic approaches for neurodegenerative diseases.
Research Areas
Acupuncture Treatment Research StudiesAlzheimer'S Disease Research And TreatmentsCholinesterase And Neurodegenerative DiseasesMicrorna In Disease RegulationNeurological Disease Mechanisms And Treatments
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