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Hemant V. Chavan
Assistant Professor at Chemistry
Multicomponent Synthesis Of Heterocycles
Quinazolinone Synthesis And Applications
Synthesis And Biological Activity
Synthesis And Biological Evaluation
Synthesis And Characterization Of Heterocyclic Compounds
991
Citations
18
H-index
0
Patents
67
Publications
0
Grants
$0
Total Funding
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Research Contributions
Developed novel pyrazoline derivatives as potent anti-inflammatory and antioxidant agents.
Synthesized and evaluated 3-(substituted)-aryl-5-(9-methyl-3-carbazole)-1H-2-pyrazolines, demonstrating significant anti-inflammatory and antioxidant activity through biological evaluation and docking studies.
Bioorganic & Medicinal Chemistry Letters (2012)
Pioneered a rapid one-pot, four-component synthesis of pyranopyrazoles using heteropolyacid under solvent-free conditions.
Developed an environmentally friendly and efficient method for synthesizing pyranopyrazoles, utilizing heteropolyacid as a catalyst in solvent-free conditions, showcasing a green chemistry approach.
Bulletin of the Korean Chemical Society (2011)
Synthesized extended conjugated indolyl chalcones with anti-breast cancer, anti-inflammatory, and antioxidant properties.
Designed and synthesized novel indolyl chalcones, demonstrating their potential as multi-target agents with significant activity against breast cancer, inflammation, and oxidative stress.
Bioorganic & Medicinal Chemistry Letters (2017)
Utilized aqueous extract of Acacia concinna pods as a surfactant-type catalyst for green synthesis.
Showcased the application of a natural surfactant derived from Acacia concinna pods as an efficient and sustainable catalyst for Knoevenagel condensation reactions, leading to the synthesis of 3-carboxycoumarins and cinnamic acids.
ACS Sustainable Chemistry & Engineering (2013)
Designed and synthesized pyrazole amalgamated flavones with significant anti-inflammatory activity.
Created novel pyrazole-flavone hybrids and evaluated their anti-inflammatory properties, demonstrating a structure-activity relationship for improved therapeutic potential.
Bioorganic & Medicinal Chemistry Letters (2013)
Developed a green method for synthesizing [1,3]oxazine derivatives using thiamine hydrochloride (Vitamin B1) in water.
Introduced an environmentally benign and efficient method for synthesizing [1,3]oxazine derivatives, utilizing thiamine hydrochloride as a catalyst in aqueous media, highlighting the use of readily available and non-toxic materials.
Comptes Rendus Chimie (2013)
Explored the potential of carbazole chalcones as radical scavengers, antimicrobial, and cancer chemopreventive agents.
Synthesized novel carbazole chalcones and evaluated their biological activities, demonstrating their potential as multi-faceted therapeutic agents with radical scavenging, antimicrobial, and cancer chemopreventive properties.
Journal of Enzyme Inhibition and Medicinal Chemistry (2012)
Research Highlights
Dr. Chavan's research focuses on the synthesis and biological evaluation of heterocyclic compounds, particularly pyrazolines, chalcones, and quinazolinones, with applications in anti-inflammatory, antioxidant, and anticancer drug discovery. His work emphasizes green chemistry approaches and multicomponent reactions for efficient synthesis.
Research Areas
Multicomponent Synthesis Of HeterocyclesQuinazolinone Synthesis And ApplicationsSynthesis And Biological ActivitySynthesis And Biological EvaluationSynthesis And Characterization Of Heterocyclic Compounds
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