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Professor at Biochemistry
Ask questions about Jalaluddin A. Khan's research, publications, and ongoing work
Demonstrated the biological mechanisms linking Alzheimer’s disease and type 2 diabetes mellitus, highlighting the role of chronic inflammation in the pathogenesis of both conditions.
Synthesized and evaluated a new series of diethyl 4-substituted-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates as inhibitors against yeast α-glucosidase, offering potential therapeutic avenues for diabetes.
Evaluated the antioxidant properties of Salvadora persica (Miswak), a traditional chewing stick, highlighting its potential health benefits.
Investigated the combined effect of Lepidium Sativum and alendronate in treating glucocorticoid-induced osteoporosis in rats, demonstrating a synergistic antiosteoporotic effect.
Analyzed the levels of acetylcholinesterase and butyrylcholinesterase in patients with Alzheimer's disease and type 2 diabetes mellitus, providing insights into the neurochemical changes associated with these conditions.
Demonstrated that (-)-Epicatechin protects against CCl4-induced liver toxicity in rats by modulating oxidative stress markers.
Showed that Thymoquinone and Difluoromethylornithine (DFMO) synergistically induce apoptosis of human acute T lymphoblastic leukemia Jurkat cells through epigenetic pathway modulation.
Dr. Khan's research focuses on the interplay between metabolic disorders like diabetes and neurodegenerative diseases, with a strong emphasis on drug discovery and the exploration of natural compounds for therapeutic interventions. His work also encompasses bone health, osteoporosis, and the application of mass spectrometry in biochemical analysis.
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