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Researcher at Research Department
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Demonstrated that expressing the wheat TaWRKY44 gene in transgenic tobacco plants confers tolerance to multiple abiotic stresses, including drought, salinity, and heat.
Showed that tannins improve dough mixing properties by affecting the physicochemical and structural properties of wheat gluten proteins.
Successfully enriched provitamin A content in wheat by introducing bacterial carotenoid biosynthetic genes CrtB and CrtI.
Utilized CRISPR/Cas9 technology to efficiently generate myostatin gene-mutated rabbits, demonstrating the potential for gene editing in livestock.
Demonstrated that CRISPR/Cas9-mediated knockout of the GJA8 gene in rabbits effectively models human congenital cataracts, providing a valuable tool for studying this disease.
Engineered wheat to enhance provitamin A content by simultaneously overexpressing the CrtB gene and silencing the carotenoid hydroxylase (TaHYD) gene.
Developed radiopaque and uniform alginate microspheres loaded with tantalum nanoparticles for real-time imaging during transcatheter arterial embolization.
Characterized SMN copy number variations in a Chinese population to improve carrier screening and diagnosis of spinal muscular atrophy.
Jian Zeng's research focuses on plant genetics and molecular biology, particularly in enhancing stress tolerance and nutritional content in crops like wheat and cassava. His work also encompasses molecular diagnostics of genetic disorders and the development of novel biomaterials for medical applications.
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