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Ph.D. student at Strahlenklinik
Ask questions about Jian‐Guo Zhou's research, publications, and ongoing work
Demonstrated that miR-508-5p regulates multidrug resistance of gastric cancer cells by targeting ABCB1 and ZNRD1, contributing to a better understanding of chemoresistance mechanisms.
Created and validated a 15-long non-coding RNA (lncRNA) signature that predicts survival outcomes and functions as a competing endogenous RNA (ceRNA) in patients with colorectal cancer.
Developed and prospectively validated a liquid immune profile-based signature (LIPS) to predict the response of patients with recurrent/metastatic cancer to immune checkpoint inhibitors, improving patient selection for immunotherapy.
Conducted a meta-analysis demonstrating that human milk feeding is a protective factor against retinopathy of prematurity (ROP) in preterm infants, highlighting the importance of human milk in neonatal care.
Showed that low-dose radiation therapy, particularly with 0.5 Gy, improves pain in degenerative joint disease of the fingers, offering a potential alternative treatment option.
Identified novel key long non-coding RNAs (lncRNAs) involved in periodontitis using weighted gene co-expression network analysis, providing insights into the molecular mechanisms of periodontal disease.
Dissected tumor antigens and immune subtypes of glioma to develop mRNA vaccine, paving the way for personalized immunotherapy approaches for glioma treatment.
Identified an endogenous retroviral signature to predict anti-PD-1 response in melanoma, enhancing the ability to predict treatment outcomes.
Jian-Guo Zhou is a Ph.D. student at Zunyi Medical University, specializing in oncology with a focus on cancer immunotherapy, biomarkers, and the development of prognostic signatures for various cancers. His research also extends to neonatal respiratory health, particularly bronchopulmonary dysplasia and retinopathy of prematurity.
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