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Researcher at Research Department
Ask questions about João Marcelo de Castro e Sousa's research, publications, and ongoing work
Conducted in vivo studies demonstrating the anticarcinogenic and antitumoral effects of phytol in Swiss mice with DMBA-induced breast cancer, contributing to the understanding of phytol's therapeutic potential.
Published a comprehensive review on the biological properties of citrinin, a mycotoxin, providing insights into its effects on various biological systems and its potential as a therapeutic agent.
Examined the pharmacological effects and toxicogenetic impacts of omeprazole, including its effects on genomic instability and cancer development, contributing to the understanding of drug-induced toxicity.
Investigated the cytotoxic and mutagenic effects of the food additive tartrazine on eukaryotic cells, contributing to the understanding of the potential health risks associated with food additives.
Studied the influence of heavy metals on toxicogenetic damage in a Brazilian tropical river, contributing to the understanding of environmental pollution and its impact on human health.
Investigated the antitumor effects of alpha-terpineol in preclinical studies, contributing to the development of new cancer therapies.
Evaluated the cytotoxic and genotoxic potential of Guaribas river water, influenced by anthropogenic action, contributing to environmental monitoring and assessment.
Dr. João Marcelo de Castro e Sousa is a leading researcher in the field of toxicology and pharmacology, with a focus on the effects of natural compounds and synthetic substances on human health, particularly in the context of cancer and environmental health. His work explores the cytotoxic and genotoxic effects of various substances, contributing to the understanding of disease mechanisms and potential therapeutic interventions.
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