Researchers
Discover all researchers in life sciences
Loading researchers...
Kaiyue Zhao
Researcher at Research Department
Alzheimer'S Disease Research And Treatments
Circular Rnas In Diseases
Microrna In Disease Regulation
Neuroinflammation And Neurodegeneration Mechanisms
Neurological Disease Mechanisms And Treatments
285
Citations
10
H-index
0
Patents
32
Publications
0
Grants
$0
Total Funding
AI Research AssistantBeta
Ask questions about Kaiyue Zhao's research, publications, and ongoing work
What are their main research contributions?
Show me their collaboration network
What grants fund their research?
Research Contributions
miR-148a-3p/p35/PTEN Signaling in Alzheimer's Disease
Identified the implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer’s disease, suggesting potential therapeutic targets.
Molecular Therapy — Nucleic Acids (2021)
Tilianin Ameliorates Cognitive Dysfunction in Vascular Dementia
Demonstrated that Tilianin improves cognitive function and reduces neuronal damage in a rat model of vascular dementia through p-CaMKII/ERK/CREB and ox-CaMKII-dependent MAPK/NF-κB pathways.
Oxidative Medicine and Cellular Longevity (2021)
miR-30a-5p Induces Aβ Production in Alzheimer's Disease
Showed that miR-30a-5p induces amyloid-beta (Aβ) production by inhibiting the nonamyloidogenic pathway in Alzheimer’s disease, contributing to the understanding of disease mechanisms.
Pharmacological Research (2022)
miR-25802/KLF4/NF-κB Axis in Microglia-Mediated Neuroinflammation
Discovered that the miR-25802/KLF4/NF-κB signaling axis regulates microglia-mediated neuroinflammation in Alzheimer’s disease, highlighting a potential target for therapeutic intervention.
Brain Behavior and Immunity (2024)
Tilianin Targets Inflammatory and Apoptotic Pathways in Vascular Dementia
Revealed that Tilianin improves cognition in a vascular dementia rodent model by targeting miR-193b-3p/CaM- and miR-152-3p/CaMKIIα-mediated inflammatory and apoptotic pathways.
Frontiers in Immunology (2023)
Role of Traditional Chinese Medicine in Neurodegenerative Diseases
Explored the role of traditional Chinese medicine in ameliorating mitochondrial dysfunction via non-coding RNA signaling, with implications for treating neurodegenerative diseases.
Frontiers in Pharmacology (2023)
GAS5 as a ceRNA in Alzheimer's Disease
Demonstrated that long noncoding RNA GAS5 acts as a competitive endogenous RNA to regulate GSK-3β and PTEN expression by sponging miR-23b-3p in Alzheimer’s disease.
Neural Regeneration Research (2024)
Research Highlights
Kaiyue Zhao investigates the roles of non-coding RNAs, particularly microRNAs and circular RNAs, in the pathogenesis of neurological diseases such as Alzheimer's disease and vascular dementia, seeking novel therapeutic targets. Her research explores molecular mechanisms and potential treatments using both in vitro and in vivo models.
Research Areas
Alzheimer'S Disease Research And TreatmentsCircular Rnas In DiseasesMicrorna In Disease RegulationNeuroinflammation And Neurodegeneration MechanismsNeurological Disease Mechanisms And Treatments
Similar Researchers You Should Know
Researchers with overlapping expertise and complementary work
Finding similar researchers...