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Liang Li
Researcher at Research Department
Congenital Anomalies And Fetal Surgery
Gene Expression And Cancer Classification
Immune Cell Function And Interaction
Immunology
Parasitic Infections In Humans And Animals
7.0K
Citations
45
H-index
0
Patents
100
Publications
0
Grants
$0
Total Funding
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Research Contributions
Role of EGFR in Liver Macrophages during Hepatocellular Carcinoma
Identified the tumor-promoting role of EGFR in liver macrophages during the formation of hepatocellular carcinoma, providing insights into potential therapeutic targets.
Nature Cell Biology (2014)
Regulation of Laryngeal Squamous Cell Cancer Progression
Investigated the role of the lncRNA H19/miR-148a-3p/DNMT1 axis in regulating the progression of laryngeal squamous cell cancer, offering potential therapeutic avenues.
Oncotarget (2016)
Single-cell and spatial transcriptome analysis of liver metastatic colorectal cancer
Performed single-cell and spatial transcriptome analysis to reveal the cellular heterogeneity of liver metastatic colorectal cancer, advancing the understanding of cancer progression.
Science Advances (2023)
Hypoxia-induced ZEB1 promotes cervical cancer progression
Demonstrated that hypoxia-induced ZEB1 promotes cervical cancer progression via CCL8-dependent tumor-associated macrophage recruitment, highlighting a key mechanism in tumor development.
Cell Death and Disease (2019)
Immune Exhaustion of T Cells in Alveolar Echinococcosis
Studied immune exhaustion of T cells in alveolar echinococcosis patients and its reversal by blocking checkpoint receptor TIGIT, offering potential therapeutic strategies.
Hepatology (2019)
Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration
Showed that tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC.
Journal of Experimental & Clinical Cancer Research (2021)
Targeting OXCT1-mediated ketone metabolism reprograms macrophages to promote antitumor immunity
Demonstrated that targeting OXCT1-mediated ketone metabolism reprograms macrophages to promote antitumor immunity via CD8+ T cells in hepatocellular carcinoma.
Journal of Hepatology (2024)
Research Highlights
Dr. Liang Li is a leading researcher in cancer immunotherapy and diagnostics, with significant contributions to understanding tumor microenvironments and developing novel therapeutic strategies. His work has advanced the field of precision medicine and improved patient outcomes.
Research Areas
Congenital Anomalies And Fetal SurgeryGene Expression And Cancer ClassificationImmune Cell Function And InteractionImmunologyParasitic Infections In Humans And Animals
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