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Man‐Li Luo
Researcher at Research Department
Cancer-Related Gene Regulation
Cancer-Related Molecular Mechanisms Research
Phytochemicals And Antioxidant Activities
Postharvest Quality And Shelf Life Management
Signaling Pathways In Disease
4.5K
Citations
31
H-index
0
Patents
87
Publications
0
Grants
$0
Total Funding
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Research Contributions
CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance
Identified that CD10+GPR77+ cancer-associated fibroblasts promote cancer formation and chemoresistance by sustaining cancer stemness.
Cell (2018)
Active Pin1 as a Key Target of All-Trans Retinoic Acid in Acute Promyelocytic Leukemia and Breast Cancer
Demonstrated that active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer, offering potential therapeutic avenues.
Nature Medicine (2015)
Rac1 Activates Non-Oxidative Pentose Phosphate Pathway to Induce Chemoresistance of Breast Cancer
Showed that Rac1 activates the non-oxidative pentose phosphate pathway, leading to chemoresistance in breast cancer cells.
Nature Communications (2020)
Exogenous Glutathione Alleviates Chilling Injury in Postharvest Bell Pepper
Discovered that exogenous glutathione alleviates chilling injury in postharvest bell pepper by modulating the ascorbate-glutathione (AsA-GSH) cycle, improving postharvest quality.
Food Chemistry (2021)
Long noncoding RNA DIO3OS Induces Glycolytic-Dominant Metabolic Reprogramming to Promote Aromatase Inhibitor Resistance in Breast Cancer
Identified that long noncoding RNA DIO3OS induces glycolytic-dominant metabolic reprogramming, promoting aromatase inhibitor resistance in breast cancer.
Nature Communications (2022)
Inactivation of the Prolyl Isomerase Pin1 Sensitizes BRCA1-Proficient Breast Cancer to PARP Inhibition
Demonstrated that inactivation of the prolyl isomerase Pin1 sensitizes BRCA1-proficient breast cancer to PARP inhibition, suggesting a novel therapeutic strategy.
Cancer Research (2020)
Cancer cell-derived arginine fuels polyamine biosynthesis in tumor-associated macrophages to promote immune evasion
Discovered that cancer cell-derived arginine fuels polyamine biosynthesis in tumor-associated macrophages to promote immune evasion, revealing a new target for immunotherapy.
Cancer Cell (2025)
Research Highlights
Man-Li Luo is a leading researcher in cancer biology and postharvest food science, focusing on molecular mechanisms, chemoresistance, and innovative strategies to improve food quality and shelf life. Her work has significantly advanced our understanding of cancer stemness, tumor microenvironment interactions, and postharvest technologies for horticultural products.
Research Areas
Cancer-Related Gene RegulationCancer-Related Molecular Mechanisms ResearchPhytochemicals And Antioxidant ActivitiesPostharvest Quality And Shelf Life ManagementSignaling Pathways In Disease
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