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Nahed N. E. El-Sayed - Organic Chemistry & Drug Discovery Research

Nahed N. E. El-Sayed

Associate Research Professor at Calibration and Maintenance, Administration of Technical Support

Crystallization And Solubility Studies

Drug Discovery

Synthesis And Biological Activity

Synthesis And Characterization Of Heterocyclic Compounds

X-Ray Diffraction In Crystallography

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Research Contributions

Synthesis of novel thiophene derivatives with antimicrobial activity.

Developed new thiophene-based compounds and assessed their potential as antimicrobial agents, contributing to the search for new treatments against bacterial infections.

Molecules (2016)

Design and synthesis of Schiff's bases as fenamate isosteres with analgesic and anti-inflammatory properties.

Synthesized novel Schiff's bases, exploring their potential as alternatives to existing anti-inflammatory drugs, contributing to the development of new pain management strategies.

Bioorganic & Medicinal Chemistry Letters (2014)

Investigation of the Knoevenagel reaction for the synthesis of heterocyclic compounds with anti-inflammatory and anti-ulcer activities.

Utilized the Knoevenagel reaction to create thiophene, pyrimidine, and triazole derivatives, exploring their therapeutic potential for treating inflammation and ulcers.

Steroids (2016)

Development of pyrazole derivatives with anti-tumor activities using cyanoacetylhydrazine.

Synthesized pyrazole derivatives and evaluated their anti-tumor effects, contributing to the discovery of potential cancer treatments.

Molecules (2012)

Identification of anti-SARS-CoV-2 compounds using QSAR-based virtual screening and molecular dynamics simulation.

Applied computational methods to identify potential anti-SARS-CoV-2 compounds, contributing to the fight against the COVID-19 pandemic.

Pharmaceuticals (2021)

Synthesis and evaluation of 4H-Pyran derivatives as antioxidant, antibacterial, and anti-HCT-116 cells of CRC.

Synthesized and evaluated the biological activities of 4H-Pyran derivatives, including antioxidant, antibacterial, and anticancer properties, contributing to the development of new therapeutic agents.

Pharmaceuticals (2022)

Synthesis and evaluation of anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities of some 3H-quinazolin-4-one derivatives.

Synthesized and evaluated the biological activities of 3H-quinazolin-4-one derivatives, contributing to the development of new therapeutic agents.

Journal of Enzyme Inhibition and Medicinal Chemistry (2019)

Research Highlights

Associate Research Professor specializing in synthetic organic chemistry and drug discovery, with a focus on synthesizing novel heterocyclic compounds and evaluating their biological activities, including antimicrobial, anti-inflammatory, and anticancer properties.

Research Areas

Crystallization And Solubility StudiesDrug DiscoverySynthesis And Biological ActivitySynthesis And Characterization Of Heterocyclic CompoundsX-Ray Diffraction In Crystallography

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