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Parham Taslımı
Assiatant professor at Biotechnology
Cholinesterase And Neurodegenerative Diseases
Crystallization And Solubility Studies
Enzyme Function And Inhibition
Phenothiazines And Benzothiazines Synthesis And Activities
Synthesis And Biological Activity
13.5K
Citations
70
H-index
0
Patents
100
Publications
0
Grants
$0
Total Funding
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Research Contributions
Discovery of novel bromophenol derivatives with acetylcholinesterase inhibition properties.
Synthesized and characterized novel bromophenol derivatives and evaluated their inhibitory effects on acetylcholinesterase, demonstrating potential for Alzheimer's disease treatment.
Bioorganic Chemistry (2015)
Identification of novel pyrazole derivatives as potent carbonic anhydrase and acetylcholinesterase inhibitors.
Synthesized and evaluated pyrazole derivatives, identifying potent inhibitors of carbonic anhydrase and acetylcholinesterase, with implications for various therapeutic applications.
Bioorganic Chemistry (2019)
Investigation of the antioxidant and anticholinergic properties of olivetol.
Investigated the antioxidant and anticholinergic properties of olivetol, contributing to the understanding of its potential health benefits and therapeutic applications.
Journal of Food Biochemistry (2018)
Evaluation of the antidiabetic and antiparasitic potentials of natural antioxidant compounds.
Assessed the inhibitory effects of natural antioxidant compounds on α-glycosidase, α-amylase, and human glutathione S-transferase enzymes, highlighting their antidiabetic and antiparasitic potential.
International Journal of Biological Macromolecules (2018)
Synthesis and evaluation of novel benzenesulfonamides as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors.
Synthesized and characterized novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs, demonstrating their inhibitory effects on acetylcholinesterase, α-glycosidase, and carbonic anhydrase.
Bioorganic Chemistry (2020)
Exploration of the effects of hesperidin on metabolic enzymes in rats.
Studied the effects of hesperidin on sodium arsenite-induced organ toxicity in rats, focusing on metabolic enzymes and its potential as an antidiabetic and anticholinergic agent.
Journal of Food Biochemistry (2018)
Discovery of novel diarylmethanon, bromophenol and diarylmethane compounds as inhibitors.
Identified potent aldose reductase, α-amylase and α-glycosidase inhibitors, offering a new therapeutic approach in diabetes and functional hyperglycemia.
International Journal of Biological Macromolecules (2018)
Research Highlights
Dr. Parham Taslımı is a biotechnology researcher specializing in the synthesis and biological evaluation of novel compounds, with a focus on enzyme inhibition and drug discovery for various diseases, including Alzheimer's and diabetes.
Research Areas
Cholinesterase And Neurodegenerative DiseasesCrystallization And Solubility StudiesEnzyme Function And InhibitionPhenothiazines And Benzothiazines Synthesis And ActivitiesSynthesis And Biological Activity
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