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Rui Liu
Senior Scientist & Supervisor of Postgraduate at Organic Chemistry and Function Research
Alzheimer'S Disease Research And Treatments
Cancer-Related Molecular Mechanisms Research
Circular Rnas In Diseases
Microrna In Disease Regulation
Neuroinflammation And Neurodegeneration Mechanisms
12.8K
Citations
61
H-index
0
Patents
100
Publications
0
Grants
$0
Total Funding
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Research Contributions
Identified a five-microRNA signature for gastric cancer diagnosis.
Developed a serum microRNA expression profile that serves as a biomarker for the diagnosis of gastric cancer, improving early detection and prognosis.
European Journal of Cancer (2010)
Investigated the role of the PI3K/AKT pathway in multidrug resistance in cancers.
Examined the PI3K/AKT pathway as a key link in modulating the multidrug resistance of cancers, providing insights into potential therapeutic targets.
Cell Death and Disease (2020)
Developed a novel probe for labile Fe2+ detection and cell imaging.
Created an ICT-based two-photon and NIR fluorescent probe for the detection of labile Fe2+ and cell imaging in living cells, advancing diagnostic capabilities.
Sensors and Actuators B Chemical (2019)
Demonstrated the neuroprotective effects of Apigenin in an Alzheimer's disease mouse model.
Showed that Apigenin has neuroprotective, anti-amyloidogenic, and neurotrophic effects in an Alzheimer's disease mouse model, suggesting potential therapeutic applications.
Molecules (2013)
Identified miR-143 and miR-145 as synergistic regulators of ERBB3 in breast cancer.
Demonstrated that miR-143 and miR-145 synergistically regulate ERBB3 to suppress cell proliferation and invasion in breast cancer, offering potential therapeutic targets.
Molecular Cancer (2014)
Investigated the role of circRNA in promoting metastasis of Colorectal Cancer.
Showed that hypoxia-induced exosomal circRNA promotes metastasis of Colorectal Cancer via targeting GEF-H1/RhoA axis, providing insights into cancer progression.
Theranostics (2020)
Research Highlights
Dr. Rui Liu is a Senior Scientist at the Chinese Academy of Medical Sciences & Peking Union Medical College, specializing in microRNA and circular RNA research, with significant contributions to cancer diagnostics and Alzheimer's disease treatments. Her work focuses on understanding molecular mechanisms and developing innovative therapeutic approaches.
Research Areas
Alzheimer'S Disease Research And TreatmentsCancer-Related Molecular Mechanisms ResearchCircular Rnas In DiseasesMicrorna In Disease RegulationNeuroinflammation And Neurodegeneration Mechanisms
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